Advancing innovations that benefit patients
We are pleased to announce a publication from DOCTRC!
“Dental, Oral and Craniofacial Tissue Regeneration Consortium (DOCTRC): An Infrastructure for Accelerating Regenerative Therapies from Discovery to Clinical Impact” published in the Journal of Clinical and Translational Science!
This paper outlines our integrated approach to overcoming the technical, regulatory, and clinical hurdles that often stall medical innovation, providing a scalable model for faster therapy translation.
What is the Translational Resource Center?
The “Translational Resource Center”, formerly known as the Michigan-Pittsburgh-Wyss Regenerative Medicine Resource Center, is one of the two national Resource Centers established by the National Institute of Dental and Craniofacial Research (NIDCR)’s Dental Oral and Craniofacial Tissue Regeneration Consortium (DOCTRC) initiative, under award numbers U24DE026915 & U24DE029462. With the overarching goal of developing clinical trial-ready tissue engineering/ regenerative medicine products and protocols, the DOCTRC initiative provides funding and resources through the Interdisciplinary Translational Project (ITP) program administered by the two national Resource Centers.
The Translational Resource Center brings together a multi-disciplinary team of clinicians, engineers, scientists, and technology commercialization and regulatory experts from academia and industry. This team supports the regenerative medicine research community by providing resources and expertise to guide innovations that address unmet clinical needs for the regeneration or restoration of DOC tissues. Through its Core Services and Resources, the Translational Resource Center strives to accelerate the translation of promising technologies towards clinical trials and beyond.
Collective Impact
With funding from the National Institute of Dental and Cranial Research (NIDCR), TRC brings together a multidisciplinary team from academia and industry to support the regenerative medicine research community, guide technologies towards FDA submission, and address unmet clinical needs.
At the heart of the TRC is the Interdisciplinary Translational Project (ITP) program, dedicated to shepherding promising regenerative technologies that address unmet clinical needs in dental, oral, and craniofacial healthcare. With the key metric of FDA clearances/ approvals, experts throughout the TRC provide essential translational expertise, guiding projects from research phase through preclinical development, supporting the crucial steps toward FDA submission, always with clinical adoption in mind.
To date, the TRC and its ITP teams have achieved remarkable milestones:
