Manufacturing Services

Provides researchers with specialized facilities and expertise for prototyping, process development, and production of medical devices and materials, enabling the advancement of biomedical innovations toward clinical application.

Contact translationalrc@umich.edu for more information.

Biomaterial & Particle Production

Manufacture of specialized materials and particles for biomedical applications, including:

• Biopolymer-based hydrogels and cryogels
• Polymer-based porous scaffolds
• Polymer-based nano/micro particles
• Lipid-based nano/micro particles
• Polymer-based aggregates

Analytical Expertise

Offers expertise in drug release profiling and material characterization using advanced analytical techniques and assays.

• Drug release profiling by HPLC, SEC, GPC, Ion Exchange chromatography, fluorescence, luminescence, absorbance, Native-PAGE, SDS-PAGE, Western Blots, Agarose Gels, ELISAs/Titers, LC/MS, numerous other product specific assays including cell-based assays.
• Material characterization: Dynamic light scattering, rheology, NMR, IR, SEM, TEM, numerous other product specific assays.

Translational Capabilities

Specialized support for process validation, regulatory compliance, and safety testing to advance products toward clinical use.

• Process and analytical qualification and validation
• Support good laboratory practice (GLP) toxicity & biocompatibility testing, regulatory submissions, and in some cases early-stage human clinical trials.

Available Instrumentation

• LC/MS
• Fluorescent/absorbance plate-reader
• HPLC (multiple modalities)
• Dynamic Light Scattering
• Zeta potential (Zetasizer)
• Rheometer