About Us
Reconstructing dental, oral, and craniofacial (DOC) tissues lost or damaged by disease or trauma using tissue engineering and regenerative medicine is a key goal in dentistry. While these approaches have achieved success in other areas of medicine, their application in DOC care is still emerging in clinical practice.
To meet this need, the Michigan-Pittsburgh-Wyss Regenerative Medicine (MPWRM) Resource Center, rebranded as the Translational Resource Center (TRC) in 2024, was established as an interdisciplinary partnership amongst the University of Michigan, the University of Pittsburgh, and the Wyss Institute, along with technology, clinical, regulatory, marketing, and commercial translation experts from private practice and industry. Through this collaborative effort, we accelerate clinical adoption of promising technologies by providing the interdisciplinary expertise and resources to guide technologies towards clinical adoption.
Mission
Our mission is to strategically partner with scientists, engineers and clinicians to translate dental, oral and craniofacial tissue engineering and regenerative medicine technologies to the clinical marketplace. We assist by building a customized approach for success utilizing an innovative toolkit, access to an exclusive mentorship and an expansive community of translational resources.
History of the Translational Resource Center
Michigan-Pittsburgh-Wyss Regenerative Medicine Resource Center is established
With U24 funding support from NIDCR (Stage 2 of DOCTRC program), Michigan-Pittsburgh-Wyss Regenerative Medicine (MPWRM) Resource Center is established as an interdisciplinary partnership amongst the University of Michigan, the University of Pittsburgh, and the Wyss Institute, along with technology, clinical, regulatory, marketing, and commercial translation experts from private practice and industry
Interdisciplinary Translational Project program launched
In January 2018, the MPWRM Resource Center funded its first cohort of ITPs
Second cohort of ITPs join the MPWRM Resource Center
In September 2018, a second cohort of projects were selected for the ITP program
Third cohort of ITPs join the MPWRM Resource Center
In March 2019, a third cohort of projects were selected for the ITP program
MPWRM Resource Center is awarded additional funding support from NIDCR
MPWRM Resource Center enters Stage 3 of the DOCTRC program with additional funding support from NIDCR, to continue to shepherd promising dental, oral, craniofacial technologies towards clinical adoption
Fourth cohort of ITPs join the MPWRM Resource Center
In November 2021, a fourth cohort of projects were selected for the ITP program
Fifth cohort of ITPs join the MPWRM Resource Center
In May 2023, a fourth cohort of projects were selected for the ITP program
MPWRM Resource Center rebrands as the Translational Resource Center
Our new look and feel embodies our commitment to advancing technology translation, and represents the dynamic nature of our work as well as oru vision for the future




