Current Portfolio
Translational Resource Center created and uses the Translational Development Status Questionnaire as a reporting tool capture the overall development status of its projects. Divided into 5 key phases, the questionnaire provides a high level overview on the translational maturity of the project based on multitude of key deliverables. For details, please see our publication J Dent Res. 2021
| Research | Development | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pre-clinical | Clinical | |||||||||
| Tissue Addressed | Project | Technology Type | Regulatory Path | Team | Phase 1 Research & Planning | Phase 2 Feasibility | Phase 3 Verification | Phase 4 GLP Validation | Phase 5 IND/IDE/510(k) preparation | |
| Bone | Ostiio: A Smart, Fully-Implantable CMF Distractor | Device | 510(k) | Ostiio | ||||||
| Bone | TETRANITE®: Optimization of a Novel Organic-Mineral Bone Adhesive for Dental Bone Grafting | Combination (device/ drug) | IDE | RevBio | ||||||
| Salivary Gland | Non-Viral Aquaporin-1 Gene Therapy to Restore Salivary Flow | Biologic | IND | Isabelle Lombaert (University of Michigan) | ||||||
| Soft Tissue | Suture-less Trigeminal Nerve Repair Device | Device | 510(k) | Amend Surgical | ||||||
| Soft Tissue | Amend Tissue Tape™ for Oral Wound Care | Device | 510(k) | Amend Surgical | ||||||
| Teeth/ Dental Pulp | Commercialization of Vital-Dent | Device | 510(k) | Juan Taboas, Herb Ray (University of Pittsburgh) | ||||||
| Teeth/ Dental Pulp | Targeted Remineralization Treatment Using Mineral Loaded Starch Nanoparticles | Device | Class 1, 510(k), Monograph, De Novo | GreenMark Biomedical Inc. | ||||||
| Teeth/ Dental Pulp | RegendoGEL: A Bioinspired Hydrogel System for Endodontic Therapy | Device | IDE | Luiz Bertassoni (Oregon Health & Science University) / Pamela Yelick (Tufts University) | ||||||
For any questions/interests in the projects, please contact us at
translationalrc@umich.edu